See you most Wednesdays at 0830 on Zoom by clicking here (password 624445). Also have a look at the ICU Trials App on iOS or Android.

PROSEVA (click to read original paper)

  • High volume = high benefit?
  • Too good to be true?
  • Self-selected groups?

CITRIS-AL (click to read original paper)

  • Vic C and the start of evidence
  • Primary end points are political
  • Syndrome + syndrome

FRAIL-FIT (click to read original paper)

  • Invisible women?
  • Cause vs effect
  • Binary cut off using a hover.

SMART (click to read the original paper)

  • Why is everything sometimes less?
  • The blind following the blind?
  • Why are subgroups sub-optimal?

Now read https://emcrit.org/pulmcrit/smart/ and https://www.thebottomline.org.uk/summaries/icm/smart/.


RESCUE-ICP (click to read the original paper)

  • Why is timing is everything (this vs DECRA)?
  • What is the good life?